Hydrochloric Acid → HCID 20398034, 화합물

HRID 462392노트

반응식

HRID 462392 반응식
C[O:2][C:3](=[O:22])[CH2:4][CH2:5][CH:6]=[C:7]=[CH:8][CH2:9][S:10][CH2:11][CH2:12][CH2:13][CH2:14][CH2:15][CH2:16][CH2:17][CH2:18][CH2:19][CH2:20][CH3:21].O.[OH-].[Li+].Cl>C(O)C>[C:3]([OH:22])(=[O:2])[CH2:4][CH2:5][CH:6]=[C:7]=[CH:8][CH2:9][S:10][CH2:11][CH2:12][CH2:13][CH2:14][CH2:15][CH2:16][CH2:17][CH2:18][CH2:19][CH2:20][CH3:21]

참가 물질

6

반응물 4

HCID 313Hydrochloric AcidHCID 962WaterHCID 3939Lithium HydroxideHCID 20397918HCID 20397918, 화합물

생성물 1

HCID 20398034HCID 20398034, 화합물수율 59.7%

시약·촉매·용매 1

HCID 702Ethanol용매

실험 절차

Methyl-8-thianonadeca-4,5-dienoate (210 mg) was treated in 10 ml of ethanol and 1 ml of water with 160 mg of lithium hydroxide at room temperature for 18 hours. The solution was acidified to pH 4 with dilute HCl and extracted with diethyl ether twice. The ethereal extracts were washed with brine and dried over potassium carbonate to give 120 mg of 8-thianonadeca-4,5-dienoic acid. This procedure can be used to convert the compounds of Example VI to their corresponding acid.

후처리

  1. extractionextracted with diethyl ether twice
  2. washThe ethereal extracts were washed with brine
  3. dry with materialdried over potassium carbonate

출처 및 근거

ORD 기록
ord-671f7947c6a8469d886ab0ab0a9f6fc3
출처 데이터셋
uspto-grants-1985_05
특허 번호
US04515727

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