Propylene Oxide → N-Chlorophthalimide

HRID 46729

반응식

HRID 46729 반응식
[C:1]1(=[O:11])[NH:5][C:4](=[O:6])[C:3]2=[CH:7][CH:8]=[CH:9][CH:10]=[C:2]12.C1OC1C.C(N(C(C)C)CC)(C)C.[Cl:25]Cl>C(Cl)Cl>[Cl:25][N:5]1[C:1](=[O:11])[C:2]2=[CH:10][CH:9]=[CH:8][CH:7]=[C:3]2[C:4]1=[O:6]

참가 물질

6

반응물 4

HCID 6378Propylene OxideHCID 6809PhthalimideHCID 24526ChlorineHCID 81531Diisopropylethylamine

생성물 1

HCID 18997N-Chlorophthalimide

시약·촉매·용매 1

HCID 6344Dichloromethane용매

실험 절차

To 150 ml. of dry methylene chloride were added 7.35 g. (0.05 mole) of phthalimide followed by 17.5 ml. (5 equiv.) of propylene oxide and 0.065 g. (0.5 mmoles) of diisopropylethylamine. The mixture was cooled to 0° C. and saturated with chlorine. The mixture was stirred for about 24 hours to provide approximately 50% conversion to N-chlorophthalimide.

출처 및 근거

ORD 기록
ord-30bcf861e6db4b1091088b181ae54e82
출처 데이터셋
uspto-grants-1979_11
특허 번호
US04175082

연결된 노트

불러오는 중…