HCID 86744990, 화합물 → Alendronic Acid

HRID 467329

반응식

HRID 467329 반응식
C[CH:2]([CH2:17][N:18]1C(=O)C2=CC=CC=C2C1=O)[C:3](C)(C)[C:4](C)([P:10]([OH:13])([OH:12])=[O:11])[O:5]P(O)(O)=O>Cl>[NH2:18][CH2:17][CH2:2][CH2:3][C:4]([P:10](=[O:11])([OH:12])[OH:13])([P:10](=[O:11])([OH:13])[OH:12])[OH:5]

참가 물질

3

반응물 1

HCID 86744990HCID 86744990, 화합물

생성물 1

HCID 2088Alendronic Acid

시약·촉매·용매 1

HCID 313Hydrochloric Acid용매

실험 절차

Tetramethyl-1,1-bisphosphono-1-hydroxy-4-phthalimidobutane 40 g (0.091 mole) from Step 4 was dissolved in 200 ml of 6N HCl and the solution refluxed for 18 hours.

후처리

  1. temperaturethe solution refluxed for 18 hours

출처 및 근거

ORD 기록
ord-23af33d53d694564a4d85c5344e477be
출처 데이터셋
uspto-grants-1992_10
특허 번호
US05159108

연결된 노트

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