Methane → 4-Amino-6-(1-methylcyclopropyl)-3-methylthio-1,2,4-triazin-5-one
반응식
[NH2:1][N:2]1[C:7](=[O:8])[C:6]([C:9]2([CH3:12])[CH2:11][CH2:10]2)=[N:5][N:4]=[C:3]1[SH:13].[CH4:14].CI>[OH-].[Na+]>[NH2:1][N:2]1[C:7](=[O:8])[C:6]([C:9]2([CH3:12])[CH2:10][CH2:11]2)=[N:5][N:4]=[C:3]1[S:13][CH3:14]참가 물질
5
실험 절차
198 grams of the compound obtained according to (b) were dissolved in 500 ml of 2 normal NaOH and treated with 500 ml of methane and 150 grams of methyl iodide. The mixture was stirred for 6 hours at 20° to 30° C. The crystals formed were filtered off with suction, washed and dried. There are obtained 174.5 grams of final product (dried in a vacuum at 40° C.), white crystals, M.P. 115° to 116° C.
후처리
- customThe crystals formed
- filtrationwere filtered off with suction
- washwashed
- customdried
출처 및 근거
- ORD 기록
- ord-5466c7e1b96f44aa85af8215829ebd59
- 출처 데이터셋
- uspto-grants-1979_11
- 특허 번호
- US04175188
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