Methanethiol → Ethyl 2-[(methylsulfanyl)methyl]prop-2-enoate
반응식
[CH3:1][SH:2].[Na].[CH2:4]([O:6][C:7](=[O:12])[C:8]([CH2:10]Br)=[CH2:9])[CH3:5]>C(O)C.O>[CH2:4]([O:6][C:7](=[O:12])[C:8]([CH2:10][S:2][CH3:1])=[CH2:9])[CH3:5]참가 물질
6
실험 절차
A solution of methylmercaptan (4.8 g.) and sodium (2.3 g.) in absolute ethanol (75 ml.) is added dropwise to a solution of ethyl-2-bromomethylacrylate (19.3 g.) in ethanol (25 ml.). After two hours, it is diluted with water (400 ml.) and extracted with methylene chloride. The organic layer is dried and concentrated to dryness in vacuo to yield ethyl-2-methylthiomethylacrylate.
후처리
- extractionextracted with methylene chloride
- customThe organic layer is dried
- concentrationconcentrated to dryness in vacuo
출처 및 근거
- ORD 기록
- ord-4a61041afbef48b3896e65e216918e56
- 출처 데이터셋
- uspto-grants-1979_11
- 특허 번호
- US04176235
반응 노트
불러오는 중…