Ethanol → Ethyl caprate

HRID 477319

반응식

HRID 477319 반응식
[C:1]([OH:12])(=[O:11])[CH2:2][CH2:3][CH2:4][CH2:5][CH2:6][CH2:7][CH2:8][CH2:9][CH3:10].S(=O)(=O)(O)O.[CH2:18](O)[CH3:19]>>[C:1]([O:12][CH2:18][CH3:19])(=[O:11])[CH2:2][CH2:3][CH2:4][CH2:5][CH2:6][CH2:7][CH2:8][CH2:9][CH3:10]

참가 물질

4

반응물 3

HCID 702EthanolHCID 1118Sulfuric AcidHCID 2969Decanoic Acid

생성물 1

HCID 8048Ethyl caprate

반응 조건

온도
20 °C

실험 절차

n-Decanoic acid (17.2 g), 36N aqueous sulphuric acid solution (3 cc) and ethanol (300 cc) are heated to boiling for 4 hours. After being cooled to a temperature in the region of 20° C., the solution is concentrated to dryness at 50° C. under vacuum (20 mm Hg; 2.7 kPa), and the residue is then taken up with dichloromethane (200 cc). The organic phase is washed with saturated aqueous sodium bicarbonate solution (2×100 cc), separated off after settling has taken place, dried over anhydrous magnesium sulphate, filtered and concentrated to dryness at 40° C. under reduced pressure (20 mm Hg; 2.7 kPa). Ethyl n-decanoate (18 g) is thereby obtained, and is used in the crude state in the subsequent syntheses.

후처리

  1. concentrationthe solution is concentrated to dryness at 50° C. under vacuum (20 mm Hg; 2.7 kPa)
  2. washThe organic phase is washed with saturated aqueous sodium bicarbonate solution (2×100 cc)
  3. customseparated off after settling
  4. dry with materialdried over anhydrous magnesium sulphate
  5. filtrationfiltered
  6. concentrationconcentrated to dryness at 40° C. under reduced pressure (20 mm Hg; 2.7 kPa)

출처 및 근거

ORD 기록
ord-71832b98d84e49c7872a4c3e2963300b
출처 데이터셋
uspto-grants-1989_12
특허 번호
US04886835

연결된 노트

불러오는 중…