1-Butanol → 1,1-Dibutoxycyclohexane

HRID 482141

반응식

HRID 482141 반응식
[C:1]1(=[O:7])[CH2:6][CH2:5][CH2:4][CH2:3][CH2:2]1.[CH2:8]([OH:12])[CH2:9][CH2:10][CH3:11]>O.O.O.O.O.O.[Cl-].[Ce+3].[Cl-].[Cl-].C1(C)C=CC=CC=1>[CH2:6]([O:7][C:1]1([O:12][CH2:8][CH2:9][CH2:10][CH3:11])[CH2:6][CH2:5][CH2:4][CH2:3][CH2:2]1)[CH2:1][CH2:2][CH3:3]

참가 물질

5

반응물 2

HCID 2631-ButanolHCID 7967Cyclohexanone

생성물 1

HCID 2437181,1-Dibutoxycyclohexane수율 185.8%

시약·촉매·용매 2

HCID 22347666cerium(III) chloride hexahydrate촉매HCID 1140Toluene용매

반응 조건

온도
25 °C

실험 절차

In a 300-ml three-necked flask, 98 g (1 mole) of cyclohexanone, 148 g (2 moles) of n-butanol, 50 g of molecular sieve 4A, 2 mg of cerium chloride hexahydrate and 40 g of toluene were charged. The resulting mixture was stirred at 25° C. under atmospheric pressure for 12 hours in a nitrogen atmosphere. After the removal of the molecular sieve 4A, the solvent (toluene) and unreacted starting materials were distilled off under reduced pressure. Distillation of the residue under reduced pressure gave 212.2 g of cyclohexanone dibutyl acetal (yield: 93.1%).

후처리

  1. customAfter the removal of the molecular sieve 4A
  2. distillationwere distilled off under reduced pressure
  3. distillationDistillation of the residue under reduced pressure

출처 및 근거

ORD 기록
ord-dae1db1790a9481699e48cfae4a326c1
출처 데이터셋
uspto-grants-1998_08
특허 번호
US05792876

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