Sodium Hydroxide → Epoprostenol Sodium

HRID 483261

반응식

HRID 483261 반응식
[OH-].[Na+:2].[Na].[CH3:4][CH2:5][CH2:6][CH2:7][CH2:8][C@H:9]([OH:28])/[CH:10]=[CH:11]/[C@@H:12]1[C@H:16]2[CH2:17]/[C:18](/[O:26][C@H:15]2[CH2:14][C@H:13]1[OH:27])=[CH:19]/[CH2:20][CH2:21][CH2:22][C:23]([OH:25])=[O:24]>C(O)C>[CH3:4][CH2:5][CH2:6][CH2:7][CH2:8][C@H:9]([OH:28])/[CH:10]=[CH:11]/[C@@H:12]1[C@H:16]2[CH2:17]/[C:18](/[O:26][C@H:15]2[CH2:14][C@H:13]1[OH:27])=[CH:19]/[CH2:20][CH2:21][CH2:22][C:23]([O-:25])=[O:24].[Na+:2]

참가 물질

5

반응물 3

HCID 14798Sodium HydroxideHCID 5282411ProstacyclinHCID 5360545Sodium

생성물 1

HCID 6364626Epoprostenol Sodium

시약·촉매·용매 1

HCID 702Ethanol용매

실험 절차

5 mg of prostacyclin methyl ester was stirred at room temperature for 8 hours in 0.2 ml of a 0.35M aqueous solution of sodium hydroxide and 0.2 ml of ethanol to prepare an aqueous solution of a sodium salt of prostacyclin.

출처 및 근거

ORD 기록
ord-88e4ea4bc69c4dedaa77967554a17734
출처 데이터셋
uspto-grants-1986_03
특허 번호
US04578482

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