2-Mercaptoethanol → 2-Isopropenyl-2-oxazoline 2-mercaptoethanol

HRID 491101

반응식

HRID 491101 반응식
[C:1]([C:4]1[O:5][CH2:6][CH2:7][N:8]=1)([CH3:3])=[CH2:2].[SH:9][CH2:10][CH2:11][OH:12].N(C(C)(C)C#N)=NC(C)(C)C#N>C1(C)C=CC=CC=1>[C:1]([C:4]1[O:5][CH2:6][CH2:7][N:8]=1)([CH3:3])=[CH2:2].[SH:9][CH2:10][CH2:11][OH:12]

참가 물질

5

반응물 3

HCID 15672-MercaptoethanolHCID 6547AzobisisobutyronitrileHCID 826512-Isopropenyl-2-oxazoline

생성물 1

HCID 866091902-Isopropenyl-2-oxazoline 2-mercaptoethanol

시약·촉매·용매 1

HCID 1140Toluene용매2회

실험 절차

2-isopropenyl-2-oxazoline and 2-mercaptoethanol are reacted in toluene at 70° C. A solution of azodiisobutyronitrile (AIBN) in toluene is added to the mixture, and the reaction continued at 70° C. for several hours. The 2-isopropenyl-2-oxazoline/2-mercaptoethanol adduct is obtained after removal of the solvent under reduced pressure. This 2-isopropenyl-2-oxazoline/2-mercaptoethanol adduct is then reacted under nitrogen with maleic anhydride in 300 mL of dimethoxyethane at 70° C. for one hour. After cooling, the contents of the reaction are poured into heptane. The resulting product is dried at 40° C. in vacuo for 24 hours.

후처리

  1. waitthe reaction continued at 70° C. for several hours

출처 및 근거

ORD 기록
ord-327845dfc3354e4d949860d626b948bb
출처 데이터셋
uspto-grants-2009_05
특허 번호
US07528404B2

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