Azobisisobutyronitrile → HCID 23033213, 화합물
반응식
[CH3:1][C:2]1[CH:3]=[CH:4][C:5]([N+:13]([O-:15])=[O:14])=[C:6]([CH:12]=1)[C:7]([N:9]([CH3:11])[CH3:10])=[O:8].[Br:16]N1C(=O)CCC1=O.N(C(C)(C)C#N)=NC(C)(C)C#N>C(Cl)(Cl)(Cl)Cl>[Br:16][CH2:1][C:2]1[CH:3]=[CH:4][C:5]([N+:13]([O-:15])=[O:14])=[C:6]([CH:12]=1)[C:7]([N:9]([CH3:10])[CH3:11])=[O:8]참가 물질
5
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- 온도
- 90 °C
실험 절차
The 5, N,N-Trimethyl-2-nitrobenzamide (4.16 g) obtained in Example 9-5b), N-bromosuccinimide (3.56 g) and 2,2′-azobisisobutyronitrile (328 mg) were suspended in carbon tetrachloride (80 mL). The suspension was stirred at 90° C. for 2 hours, filtered through a Celite pad and purified by column chromatography on silica gel with hexane:ethyl acetate=5:4 to give the title compound (602 mg).
후처리
- filtrationfiltered through a Celite pad
- custompurified by column chromatography on silica gel with hexane
출처 및 근거
- ORD 기록
- ord-1934b4dd044a4ee392ca3247fbb746b3
- 출처 데이터셋
- uspto-grants-2009_05
- 특허 번호
- US07538140B2
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