Hydrochloric Acid → 6-Quinolinecarboxylic acid, ethyl ester
반응식
[N:1]1[C:10]2[C:5](=[CH:6][C:7]([C:11]([OH:13])=[O:12])=[CH:8][CH:9]=2)[CH:4]=[CH:3][CH:2]=1.O1CCO[CH2:16][CH2:15]1.Cl>C(O)C>[N:1]1[C:10]2[C:5](=[CH:6][C:7]([C:11]([O:13][CH2:15][CH3:16])=[O:12])=[CH:8][CH:9]=2)[CH:4]=[CH:3][CH:2]=1참가 물질
5
반응 조건
- 온도
- 70 °C
실험 절차
4.9 g of quinoline-6-carboxylic acid was stirred in 80 ml of ethanol. 40 ml of dioxane containing 4 M of hydrogen chloride was added to the obtained mixture. After stirring at 70° C. overnight, the solvent was evaporated and the residue was treated with ethyl acetate as the extracting solvent by an ordinary method to obtain the title compound.
후처리
- customthe solvent was evaporated
- additionthe residue was treated with ethyl acetate as the extracting solvent by an ordinary method
출처 및 근거
- ORD 기록
- ord-39bdd5917a824cf489af4d15fa464529
- 출처 데이터셋
- uspto-grants-2004_03
- 특허 번호
- US06710056B2
반응 노트
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