Tetrahydrofuran → (1,1'-Biphenyl)-3-carboxylic acid

HRID 49940

반응식

HRID 49940 반응식
[C:1]1([C:7]2[CH:8]=[C:9]([CH:14]=[CH:15][CH:16]=2)[C:10]([O:12]C)=[O:11])[CH:6]=[CH:5][CH:4]=[CH:3][CH:2]=1.[OH-].[Na+].O1CCCC1>CO>[C:1]1([C:7]2[CH:8]=[C:9]([CH:14]=[CH:15][CH:16]=2)[C:10]([OH:12])=[O:11])[CH:2]=[CH:3][CH:4]=[CH:5][CH:6]=1

참가 물질

5

반응물 3

HCID 8028TetrahydrofuranHCID 14798Sodium HydroxideHCID 9855857Methyl 3-phenylbenzoate

생성물 1

HCID 12854(1,1'-Biphenyl)-3-carboxylic acid

시약·촉매·용매 1

HCID 887Methanol용매

실험 절차

0.90 g of methyl 3-phenylbenzoate was fed into 20 ml of a solvent mixture of aqueous solution of 2 M of sodium hydroxide, tetrahydrofuran and methanol (4/2/1) to conduct the reaction at 70° C. for 2 hours. The solvent was evaporated, and the residue was fed into 3 M of hydrochloric acid. The precipitate thus formed was taken by the filtration and dried to obtain the title compound in the form of white crystals.

후처리

  1. customthe reaction at 70° C. for 2 hours
  2. customThe solvent was evaporated
  3. customThe precipitate thus formed
  4. filtrationwas taken by the filtration
  5. customdried

출처 및 근거

ORD 기록
ord-b6d106859ae042a0be8637cd84cd0072
출처 데이터셋
uspto-grants-2004_03
특허 번호
US06710056B2

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