Hydrochloric Acid → 4-Formyl-3-methoxybenzoic acid

HRID 501812

반응식

HRID 501812 반응식
[CH:1]([C:3]1[CH:12]=[CH:11][C:6]([C:7]([O:9]C)=[O:8])=[CH:5][C:4]=1[O:13][CH3:14])=[O:2].O.Cl>CO.[OH-].[Na+]>[CH:1]([C:3]1[CH:12]=[CH:11][C:6]([C:7]([OH:9])=[O:8])=[CH:5][C:4]=1[O:13][CH3:14])=[O:2]

참가 물질

6

반응물 3

HCID 313Hydrochloric AcidHCID 962WaterHCID 10631650Methyl 4-formyl-3-methoxybenzoate

생성물 1

HCID 189595314-Formyl-3-methoxybenzoic acid수율 93.4%

시약·촉매·용매 2

HCID 887Methanol용매HCID 14798Sodium Hydroxide용매

실험 절차

1.72 g of methyl 4-formyl-3-methoxybenzoate was dissolved in 8.6 mL of methanol, to which 2.6 mL of a 20% aqueous solution of sodium hydroxide was added at room temperature, and this solution was stirred for one hour at the same temperature. The reaction mixture, to which water was added, was adjusted to pH 2 with 6M hydrochloric acid, and resultant precipitate was filtered out therefrom and washed with water to yield 1.49 g of 4-formyl-3-methoxybenzoic acid as light yellow solid.

후처리

  1. additionwas added at room temperature
  2. filtrationwas filtered out therefrom and
  3. washwashed with water

출처 및 근거

ORD 기록
ord-f300ada960e6404c8c73162ae3ae4977
출처 데이터셋
uspto-grants-2010_08
특허 번호
US07772285B2

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