Sodium hydride → 1-(2-Thienyl)cyclopent-3-ene-1-carbonitrile

HRID 502949

반응식

HRID 502949 반응식
[S:1]1[CH:5]=[CH:4][CH:3]=[C:2]1[CH2:6][C:7]#[N:8].[H-].[Na+]>CN(C=O)C>[S:1]1[CH:5]=[CH:4][CH:3]=[C:2]1[C:6]1([C:7]#[N:8])[CH2:4][CH:3]=[CH:2][CH2:6]1

참가 물질

4

반응물 2

HCID 24758Sodium hydrideHCID 728802-Thienylacetonitrile

생성물 1

HCID 653530801-(2-Thienyl)cyclopent-3-ene-1-carbonitrile

시약·촉매·용매 1

HCID 6228Dimethylformamide용매

실험 절차

Thiophene-2-acetonitrile and 1,4-dichloride-2-butene were added to a DMF solution of sodium hydride washed with hexane and the whole was reacted at room temperature to obtain 1-(2-thienyl)cyclopent-3-ene-1-carbonitrile.

후처리

  1. washwashed with hexane
  2. customthe whole was reacted at room temperature

출처 및 근거

ORD 기록
ord-8008992ec5f640278445eefa7cfdca24
출처 데이터셋
uspto-grants-2010_08
특허 번호
US07776897B2

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