Methyl iodide → Methyl 1-(2-thienyl)cyclobutanecarboxylate

HRID 502953노트

반응식

HRID 502953 반응식
[S:1]1[CH:5]=[CH:4][CH:3]=[C:2]1[C:6]1([C:10]([OH:12])=[O:11])[CH2:9][CH2:8][CH2:7]1.CI.[C:15](=O)([O-])O.[K+]>CN(C=O)C>[S:1]1[CH:5]=[CH:4][CH:3]=[C:2]1[C:6]1([C:10]([O:12][CH3:15])=[O:11])[CH2:7][CH2:8][CH2:9]1

참가 물질

5

반응물 3

HCID 6328Methyl iodideHCID 516893Potassium BicarbonateHCID 232948871-(Thiophen-2-yl)cyclobutanecarboxylic acid

생성물 1

HCID 68467379Methyl 1-(2-thienyl)cyclobutanecarboxylate

시약·촉매·용매 1

HCID 6228Dimethylformamide용매

실험 절차

1-(2-Thienyl)cyclobutanecarboxylic acid, methyl iodide, and potassium hydrogen carbonate were reacted in DMF at room temperature to obtain methyl 1-(2-thienyl)cyclobutanecarboxylate.

출처 및 근거

ORD 기록
ord-37af93649fd14a9aa76e4450f00e6ffd
출처 데이터셋
uspto-grants-2010_08
특허 번호
US07776897B2

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