Hydrochloric Acid → 2-Hydrazinylpyridine-4-carbonitrile hydrochloride salt

HRID 514338

반응식

HRID 514338 반응식
[NH:1]([C:3]1[CH:8]=[C:7]([C:9]#[N:10])[CH:6]=[CH:5][N:4]=1)[NH2:2].[ClH:11]>CCOC(C)=O>[ClH:11].[NH:1]([C:3]1[CH:8]=[C:7]([C:9]#[N:10])[CH:6]=[CH:5][N:4]=1)[NH2:2]

참가 물질

4

반응물 2

HCID 313Hydrochloric AcidHCID 201187142-Hydrazinylpyridine-4-carbonitrile

생성물 1

HCID 867254842-Hydrazinylpyridine-4-carbonitrile hydrochloride salt수율 95%

시약·촉매·용매 1

HCID 8857Ethyl Acetate용매

실험 절차

To a solution of 2-hydrazinylpyridine-4-carbonitrile (2.13 g, 16 mmol, PREPARATION 2) in EtOAc (10 mL) was added HCl (4 M in EtOAc, 15 mL) at rt. It was then stirred at rt for 30 min. The reaction mixture was filtered and washed with EtOAc and dried to give the title compound (3.13 g, 95%) as a yellow solid.

후처리

  1. filtrationThe reaction mixture was filtered
  2. washwashed with EtOAc
  3. customdried

출처 및 근거

ORD 기록
ord-a78809a1a8e44a92b3a4ade8149e844e
출처 데이터셋
uspto-grants-2015_08
특허 번호
US09107916B2

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