(+-)-2-Undecanol → 2-Methanesulfonyloxyundecane

HRID 53485

반응식

HRID 53485 반응식
[CH3:1][S:2]([O:5][CH:6]([CH2:8][CH2:9][CH2:10][CH2:11][CH2:12][CH2:13][CH2:14][CH3:15])[CH3:7])(=[O:4])=[O:3].[CH3:16]C(O)CCCCCCCCC.CS(Cl)(=O)=O.C(N(C(C)C)CC)(C)C>C(Cl)Cl>[CH3:1][S:2]([O:5][CH:6]([CH2:8][CH2:9][CH2:10][CH2:11][CH2:12][CH2:13][CH2:14][CH2:15][CH3:16])[CH3:7])(=[O:4])=[O:3]

참가 물질

6

반응물 4

HCID 15448(+-)-2-UndecanolHCID 31297Methanesulfonyl chlorideHCID 81531DiisopropylethylamineHCID 14916009Decan-2-yl methanesulfonate

생성물 1

HCID 153433162-Methanesulfonyloxyundecane수율 95%

시약·촉매·용매 1

HCID 6344Dichloromethane용매

실험 절차

2-Methanesulfonyloxyundecane was prepared as described for 2-methanesulfonyloxydecane from 2-undecanol (30.0 ml, 144 mmol), methanesulfonylchloride (15.5 ml, 200 mmol) and diisopropylethylamine (30.8 ml, 177 mmol) in dry CH2Cl2 (240 ml). After stirring for 3.5 hrs, the reaction was processed as previously stated but at 4 times the volumes to provide 2-methanesulfonyloxyundecane (31.35 g, 95%).

후처리

  1. custom2-Methanesulfonyloxyundecane was prepared

출처 및 근거

ORD 기록
ord-5a81bd2a8d654ff5a9d31876ec213083
출처 데이터셋
uspto-grants-1997_04
특허 번호
US05620677

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