Hydrochloric Acid → HCID 86718436, 화합물

HRID 535312노트

반응식

HRID 535312 반응식
[I:1][C:2]1[CH:7]=[CH:6][C:5]([C:8]([C:11]2[CH:16]=[CH:15][C:14]([O:17][CH3:18])=[CH:13][CH:12]=2)(O)[CH3:9])=[CH:4][CH:3]=1.C(OC(=O)C)(=O)C.Cl>>[I:1][C:2]1[CH:3]=[CH:4][C:5]([C:8]([C:11]2[CH:12]=[CH:13][C:14]([O:17][CH3:18])=[CH:15][CH:16]=2)=[CH2:9])=[CH:6][CH:7]=1

참가 물질

4

반응물 3

HCID 313Hydrochloric AcidHCID 7918Acetic AnhydrideHCID 71145508HCID 71145508, 화합물

생성물 1

HCID 86718436HCID 86718436, 화합물

실험 절차

The side chain used in example 5 (1-(4-iodophenyl)-1-(4-methoxyphenyl)ethanol) (1.25 g, 2.86 mmol) was treated with acetic anhydride (13.49 ml, 143 mmol) and HCl conc (1.042 ml, 34.3 mmol) and the reaction mixture was stirred at room temperature overnight. The reaction mixture was filtered. The precipitate was washed well with n-heptane then dried in vacuo to obtain the title compound as white solid.

후처리

  1. filtrationThe reaction mixture was filtered
  2. washThe precipitate was washed well with n-heptane
  3. customthen dried in vacuo

출처 및 근거

ORD 기록
ord-cb69c39dcf5b474c9fec2c3cbd483d58
출처 데이터셋
uspto-grants-2014_10
특허 번호
US08859535B2

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