N-Cyanoacetylethylcarbamate → ethyl N-(2-cyano-3-ethoxyacryloyl)carbamate

HRID 544193

반응식

HRID 544193 반응식
[CH2:1]([O:3][C:4]([NH:6][C:7](=[O:11])[CH2:8][C:9]#[N:10])=[O:5])[CH3:2].[CH2:12]([O:14][CH:15](OCC)OCC)[CH3:13]>C(OC(=O)C)(=O)C>[C:9]([C:8](=[CH:15][O:14][CH2:12][CH3:13])[C:7]([NH:6][C:4]([O:3][CH2:1][CH3:2])=[O:5])=[O:11])#[N:10]

참가 물질

4

반응물 2

HCID 23112N-CyanoacetylethylcarbamateHCID 31214Ethyl orthoformate

생성물 1

HCID 230015ethyl N-(2-cyano-3-ethoxyacryloyl)carbamate

시약·촉매·용매 1

HCID 7918Acetic Anhydride용매

실험 절차

A mixture of N-ethoxycarbonylcyanoacetamide (42 g), triethylorthoformate (40 g) and acetic anhydride (100 ml) is heated at reflux for one hour. The reaction is allowed to stand until cool and then is filtered, washing with ether, to yield α-cyano-β-ethoxy-N-ethoxycarbonylacrylamide.

후처리

  1. temperatureis heated
  2. temperatureat reflux for one hour
  3. temperatureuntil cool
  4. filtrationis filtered
  5. washwashing with ether

출처 및 근거

ORD 기록
ord-5c80c8f8c9c545f4b671993dcdcb6e77
출처 데이터셋
uspto-grants-1984_05
특허 번호
US04448961

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