Hydroxylamine → N'-hydroxy-2-phenylethanimidamide

HRID 557997

반응식

HRID 557997 반응식
[CH2:1]([C:8]#[N:9])[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1.[NH2:10][OH:11].ON=C(N)C1C=CC=CC=1>CCO>[OH:11][N:10]=[C:8]([NH2:9])[CH2:1][C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1

참가 물질

5

반응물 3

HCID 787HydroxylamineHCID 8794PhenylacetonitrileHCID 69186N'-Hydroxybenzenecarboximidamide

생성물 1

HCID 2731007N'-hydroxy-2-phenylethanimidamide수율 81.9%

시약·촉매·용매 1

HCID 702Ethanol용매

실험 절차

Benzyl cyanide (1 g, 8.5 mmol) and hydroxylamine (50% in water, 1.04 cm3, 17 mmol, 2 eq) in EtOH (8.5 cm3) were reacted in the same manner as in the preparation of N′-hydroxybenzimidamide (EtOAc used in extraction) to give the product N′-hydroxy-2-phenylacetimidamide (1.04 g, 81.9%) as a pale yellow solid, mp 63.5-64.5° C. (lit 57-59° C.).

출처 및 근거

ORD 기록
ord-7126ea936ddf4af08606b069eb5d41bb
출처 데이터셋
uspto-grants-2011_11
특허 번호
US08062429B2

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