Phthalic Anhydride → 2-[4-(Diethylamino)-2-hydroxybenzoyl]benzoic acid

HRID 565077

반응식

HRID 565077 반응식
[CH2:1]([N:3]([CH2:11][CH3:12])[C:4]1[CH:5]=[C:6]([OH:10])[CH:7]=[CH:8][CH:9]=1)[CH3:2].[C:13]1(=[O:23])[O:18][C:16](=[O:17])[C:15]2=[CH:19][CH:20]=[CH:21][CH:22]=[C:14]12>C1(C)C=CC=CC=1>[C:16]([C:15]1[CH:19]=[CH:20][CH:21]=[CH:22][C:14]=1[C:13]([C:7]1[CH:8]=[CH:9][C:4]([N:3]([CH2:1][CH3:2])[CH2:11][CH3:12])=[CH:5][C:6]=1[OH:10])=[O:23])([OH:18])=[O:17]

참가 물질

4

반응물 2

HCID 6811Phthalic AnhydrideHCID 70623-(Diethylamino)phenol

생성물 1

HCID 798782-[4-(Diethylamino)-2-hydroxybenzoyl]benzoic acid

시약·촉매·용매 1

HCID 1140Toluene용매

실험 절차

2-(2′-Carboxybenzoyl)-5-diethylaminophenol was prepared as follows. A mixture of m-diethylaminophenol (1 mole) and phthalic anhydride (1.2 moles) was refluxed in toluene (2.0 L) for about 16 hours, cooled, and the resulting solid filtered, washed with toluene and dried to give 2-(2′-carboxybenzoyl)-5-diethylaminophenol in 70% yield.

후처리

  1. custom2-(2′-Carboxybenzoyl)-5-diethylaminophenol was prepared
  2. temperaturecooled
  3. filtrationthe resulting solid filtered
  4. washwashed with toluene
  5. customdried

출처 및 근거

ORD 기록
ord-6101d14e85e44ff5aac0ecc59b3cd271
출처 데이터셋
uspto-grants-2001_01
특허 번호
US06169185A

연결된 노트

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