Tetrahydrophthalic anhydride → 2-Octadecyl-4,7,3a,7a-tetrahydroisoindole-1,3-dione
반응식
[CH2:1]([NH2:19])[CH2:2][CH2:3][CH2:4][CH2:5][CH2:6][CH2:7][CH2:8][CH2:9][CH2:10][CH2:11][CH2:12][CH2:13][CH2:14][CH2:15][CH2:16][CH2:17][CH3:18].[C:20]1(=O)[CH:28]2[CH:23]([CH2:24][CH:25]=[CH:26][CH2:27]2)[C:22](=[O:29])[O:21]1>>[CH2:1]([N:19]1[C:20](=[O:21])[CH:28]2[CH:23]([CH2:24][CH:25]=[CH:26][CH2:27]2)[C:22]1=[O:29])[CH2:2][CH2:3][CH2:4][CH2:5][CH2:6][CH2:7][CH2:8][CH2:9][CH2:10][CH2:11][CH2:12][CH2:13][CH2:14][CH2:15][CH2:16][CH2:17][CH3:18]참가 물질
3
반응 조건
- 온도
- 110 °C
실험 절차
Octadecylamine (5.31 g) was added to 4,7,3a,7a-tetrahydroisobenzofuran-1,3-dione (3.00 g). After being stirred for 2 hours at 110° C., the reaction mixture was purified by silica gel column chromatography (silica gel 80 g, chloroform), thereby yielding the entitled compound (7.85 g) as yellow crystals.
후처리
- customthe reaction mixture was purified by silica gel column chromatography (silica gel 80 g, chloroform)