3-(3-Nitrophenyl)pyridine → 3-(Pyridin-3-yl)aniline

HRID 581972

반응식

HRID 581972 반응식
[N:1]1[CH:6]=[CH:5][CH:4]=[C:3]([C:7]2[CH:8]=[C:9]([N+:13]([O-])=O)[CH:10]=[CH:11][CH:12]=2)[CH:2]=1>C(O)C.[Ni]>[N:1]1[CH:6]=[CH:5][CH:4]=[C:3]([C:7]2[CH:8]=[C:9]([CH:10]=[CH:11][CH:12]=2)[NH2:13])[CH:2]=1

참가 물질

4

반응물 1

HCID 121813273-(3-Nitrophenyl)pyridine

생성물 1

HCID 4595213-(Pyridin-3-yl)aniline

시약·촉매·용매 2

HCID 935Nickel촉매HCID 702Ethanol용매

실험 절차

3-(3-pyridyl)-nitrobenzene (9.1 g, 45.5 mmol) in ethanol (125 ml) is hydrogenated at ambient pressure for 1.75 hours using Raney Nickel as the catalyst. Filtration of the resulting solution through celite followed by evaporation of solvent quantitatively yields 3-(3-pyridyl)aniline.

후처리

  1. filtrationFiltration of the resulting solution through celite
  2. customfollowed by evaporation of solvent quantitatively yields 3-(3-pyridyl)aniline

출처 및 근거

ORD 기록
ord-e2c51de4f901493c8a5c8e21efe583c1
출처 데이터셋
uspto-grants-1999_07
특허 번호
US05922724

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