Phosphorus oxychloride → 2,6,7-Trichloro-3-methylquinoxaline
반응식
O=P(Cl)(Cl)[Cl:3].[Cl:6][C:7]1[CH:8]=[C:9]2[C:14](=[CH:15][C:16]=1[Cl:17])[NH:13][C:12](=O)[C:11]([CH3:19])=[N:10]2>CN(C)C1C=CN=CC=1>[Cl:3][C:12]1[C:11]([CH3:19])=[N:10][C:9]2[C:14](=[CH:15][C:16]([Cl:17])=[C:7]([Cl:6])[CH:8]=2)[N:13]=1참가 물질
4
실험 절차
POCl3 was added to 6,7-Dichloro-3-methyl-1H-quinoxalin-2-one (10 g, 44 mmol) and 4-dimethylaminopyridine (1 g) and the mixture was refluxed for 0.5 hours. After cooling, the mixture was poured onto ice (500 ml), filtered and washed with water to afford the title compound.
후처리
- temperaturethe mixture was refluxed for 0.5 hours
- temperatureAfter cooling
- additionthe mixture was poured onto ice (500 ml)
- filtrationfiltered
- washwashed with water
출처 및 근거
- ORD 기록
- ord-aa24519db1d843c2a38169ddc639d1c3
- 출처 데이터셋
- uspto-grants-2005_08
- 특허 번호
- US06927214B1
반응 노트
불러오는 중…