Hydrogen Bromide → 2-(3,4-Dichlorophenyl)-6,7-dinitroquinoxaline

HRID 584676

반응식

HRID 584676 반응식
Br.[CH3:2][C:3]([C:5]1[CH:10]=[CH:9][C:8]([Cl:11])=[C:7]([Cl:12])[CH:6]=1)=O.[N+:13]([C:16]1[C:21]([N+:22]([O-:24])=[O:23])=[CH:20][C:19]([NH2:25])=[C:18]([NH2:26])[CH:17]=1)([O-:15])=[O:14]>CS(C)=O>[Cl:12][C:7]1[CH:6]=[C:5]([C:3]2[CH:2]=[N:26][C:18]3[C:19](=[CH:20][C:21]([N+:22]([O-:24])=[O:23])=[C:16]([N+:13]([O-:15])=[O:14])[CH:17]=3)[N:25]=2)[CH:10]=[CH:9][C:8]=1[Cl:11]

참가 물질

5

반응물 3

HCID 260Hydrogen BromideHCID 75841Ethanone, 1-(3,4-dichlorophenyl)-HCID 44419034,5-Dinitrobenzene-1,2-diamine

생성물 1

HCID 223412132-(3,4-Dichlorophenyl)-6,7-dinitroquinoxaline

시약·촉매·용매 1

HCID 679Dimethyl Sulfoxide용매

반응 조건

온도
55 °C

실험 절차

48% aqueous HBr (8.8 M) (3.4 ml, 30 mmol) was slowly added to a stirred solution of 3,4-dichloroacetophenone (1.89 g, 10 mmol) in DMSO (17 ml). The solution was stirred in an open flask at 55° C. for 24 hours. The solution was poured onto ice, the solid product was filtered, washed with water, and redissolved in ethanol (18 ml). 4,5-Dinitro-1,2-phenylene-diamine (890 mg, 4.5 mmol) was added and the mixture was heated to reflux for 4 hours.

후처리

  1. additionThe solution was poured onto ice
  2. filtrationthe solid product was filtered
  3. washwashed with water
  4. dissolutionredissolved in ethanol (18 ml)
  5. temperaturethe mixture was heated
  6. temperatureto reflux for 4 hours

출처 및 근거

ORD 기록
ord-a20703e9de084538bfee31fbd1896e79
출처 데이터셋
uspto-grants-2005_08
특허 번호
US06927214B1

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