Aniline → 4-{4-[3-(4-Dimethylamino-benzoylamino)-5-fluoro-2-methyl-phenyl]-7H-pyrrolo[2,3-d]pyrimidin-6-yl}-3,6-dihydro-2H-pyridine-1-carboxylic acid dimethylamide

반응식

NC1C=CC=CC=1.[CH3:8][N:9]([CH3:36])[C:10]([N:12]1[CH2:17][CH:16]=[C:15]([C:18]2[NH:35][C:21]3[N:22]=[CH:23][N:24]=[C:25]([C:26]4[CH:31]=[C:30]([F:32])[CH:29]=[C:28]([NH2:33])[C:27]=4[CH3:34])[C:20]=3[CH:19]=2)[CH2:14][CH2:13]1)=[O:11].CCN(C(C)C)C(C)C.[CH3:46][N:47]([CH3:57])[C:48]1[CH:56]=[CH:55][C:51]([C:52](Cl)=[O:53])=[CH:50][CH:49]=1>C(Cl)Cl.N1C=CC=CC=1.CN(C1C=CN=CC=1)C>[CH3:36][N:9]([CH3:8])[C:10]([N:12]1[CH2:13][CH:14]=[C:15]([C:18]2[NH:35][C:21]3[N:22]=[CH:23][N:24]=[C:25]([C:26]4[CH:31]=[C:30]([F:32])[CH:29]=[C:28]([NH:33][C:52](=[O:53])[C:51]5[CH:50]=[CH:49][C:48]([N:47]([CH3:46])[CH3:57])=[CH:56][CH:55]=5)[C:27]=4[CH3:34])[C:20]=3[CH:19]=2)[CH2:16][CH2:17]1)=[O:11]