Uric Acid → 7,9-Dihydro-1H-purine-2,6,8(3H)-trione, monosodium salt

HRID 590946

반응식

HRID 590946 반응식
[NH:1]1[C:11](=[O:12])[C:10]2[NH:9][C:7](=[O:8])[NH:6][C:5]=2[NH:4][C:2]1=[O:3].[OH-].[Na+:14]>>[C:10]12[NH:9][C:7](=[O:8])[N-:6][C:5]=1[NH:4][C:2]([NH:1][C:11]2=[O:12])=[O:3].[Na+:14]

참가 물질

3

반응 조건

온도
70 °C

실험 절차

Monosodium urate (MSU) crystals were prepared by dissolving 1.68 g of uric acid in 500 mL of 0.01 M NaOH and heating to 70° C.55,56 NaOH was added as required to maintain the pH between 7.1 and 7.2 and the solution was filtered and incubated at room temperature with slow stirring for 24 hours.

후처리

  1. temperatureto maintain the pH between 7.1 and 7.2
  2. filtrationthe solution was filtered
  3. customincubated at room temperature

출처 및 근거

ORD 기록
ord-5602e7726f004a31bc1863d79fabac39
출처 데이터셋
uspto-grants-2016_01
특허 번호
US09238018B2

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