Ethanol → 3-Methyl-8-oximino-5,6,7,8-tetrahydroquinoline
반응식
[CH3:1][C:2]1[CH:3]=[N:4][C:5]2[C:6](=O)[CH2:7][CH2:8][CH2:9][C:10]=2[CH:11]=1.Cl.[NH2:14][OH:15].[OH-].[Na+].C(O)C>O>[CH3:1][C:2]1[CH:3]=[N:4][C:5]2[C:6](=[N:14][OH:15])[CH2:7][CH2:8][CH2:9][C:10]=2[CH:11]=1참가 물질
6
실험 절차
The quinolinone (30g), hydroxylamine hydrochloride (14g), sodium hydroxide (9g), ethanol (165ml) and water (65ml) were stirred and refluxed for 2 hours. Water (100 ml) was added and the product was allowed to crystallise overnight. The crystals were removed by filtration and washed with water and dried to give 3-methyl-8-oximino-5,6,7,8-tetrahydroquinoline (27.5g) mp 188° C.
후처리
- temperaturerefluxed for 2 hours
- customto crystallise overnight
- customThe crystals were removed by filtration
- washwashed with water
- customdried
출처 및 근거
- ORD 기록
- ord-b39eca90107547c8928c916b1b98ea00
- 출처 데이터셋
- uspto-grants-1977_03
- 특허 번호
- US04011229
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