Dimethyl Sulfate → HCID 22452645, 화합물

HRID 596590노트

반응식

HRID 596590 반응식
[OH:1][C:2]1[CH:3]=[C:4]([C:12]([OH:14])=[O:13])[C:5]2[CH2:6][CH2:7][CH2:8][CH2:9][C:10]=2[CH:11]=1.[OH-].[Na+].[CH3:17]OS(OC)(=O)=O>>[CH3:17][O:1][C:2]1[CH:3]=[C:4]([C:12]([OH:14])=[O:13])[C:5]2[CH2:6][CH2:7][CH2:8][CH2:9][C:10]=2[CH:11]=1

참가 물질

4

반응물 3

HCID 6497Dimethyl SulfateHCID 14798Sodium HydroxideHCID 21450344HCID 21450344, 화합물

생성물 1

HCID 22452645HCID 22452645, 화합물

실험 절차

A mixture of 0.02 mole of 3-hydroxy-5,6,7,8-tetrahydronaphthalene-1-carboxylic acid, and 40 ml. of 2 N sodium hydroxide solution is treated with 0.04 mole of dimethylsulfate over a 5 minutes period, and the mixture is stirred for 24 hours. The mixture is washed with 3 × 50 ml. of ether and acidified with dilute hydrochloric acid. The precipitate is collected, washed with water, dried at room temperature and 100μ pressure and recrystallized from cyclohexane.

후처리

  1. washThe mixture is washed with 3 × 50 ml
  2. customThe precipitate is collected
  3. washwashed with water
  4. customdried at room temperature
  5. custom100μ pressure and recrystallized from cyclohexane

출처 및 근거

ORD 기록
ord-be87bbe540cf4fb5b9c31419c109741a
출처 데이터셋
uspto-grants-1977_03
특허 번호
US04011326

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