Propylamine → 2-methyl-N-propylalaninamide

HRID 596813

반응식

HRID 596813 반응식
[NH2:1][C:2]([CH3:8])([CH3:7])[C:3](OC)=[O:4].[CH2:9]([NH2:12])[CH2:10][CH3:11]>CO>[CH2:9]([NH:12][C:3](=[O:4])[C:2]([NH2:1])([CH3:8])[CH3:7])[CH2:10][CH3:11]

참가 물질

4

반응물 2

HCID 7852PropylamineHCID 4186341Methyl 2-amino-2-methylpropanoate

생성물 1

HCID 214480362-methyl-N-propylalaninamide

시약·촉매·용매 1

HCID 887Methanol용매

실험 절차

To a solution of 26.3 parts of methyl 2-amino-2-methylpropionate in methanol is added 70 parts of n-propylamine. The mixture is placed in a bomb and left at a temperature of 100° C. for one week. The solvents are then stripped off under reduced pressure. Distillation of the residual oil affords N1 -propyl-2-amino-2-methylpropionamide, boiling at 58° C. at 0.1 mm pressure.

후처리

  1. waitleft at a temperature of 100° C. for one week
  2. distillationDistillation of the residual oil

출처 및 근거

ORD 기록
ord-065463928e104051adfab8401ac48500
출처 데이터셋
uspto-grants-1977_03
특허 번호
US04012367

연결된 노트

불러오는 중…