Hydrochloric Acid → HCID 178505403, 화합물
반응식
F[C:2]1[CH:8]=[C:7]([F:9])[C:6]([F:10])=[CH:5][C:3]=1[NH2:4].CCO[C:14]([S-:16])=[S:15].[K+].Cl>CN(C)C=O.O>[F:10][C:6]1[C:7]([F:9])=[CH:8][C:2]2[S:15][C:14]([SH:16])=[N:4][C:3]=2[CH:5]=1참가 물질
6
반응 조건
- 온도
- 95 °C
실험 절차
A mixture of 1 g (6.80 mmol) 2,4,5-trifluoroaniline and 1.33 g (8.16 mmol) potassium ethylxanthogenate in 5 mL dry N,N-dimethylformamide was heated in a 95° C. oil bath for 7 h. The reaction mixture was cooled to room temperature and diluted with water (15 mL). The mixture was acidified with aqueous HCl 2N. The precipitate was collected by filtration, washed with water and dried to provide 0.55 g (40%) of the titled compound as a light yellow solid. MS(m/e): 201.9 (M−H+).
후처리
- temperatureThe reaction mixture was cooled to room temperature
- filtrationThe precipitate was collected by filtration
- washwashed with water
- customdried
출처 및 근거
- ORD 기록
- ord-8b9c6fe51079404f9f89c6c44a44a38b
- 출처 데이터셋
- uspto-grants-2011_03
- 특허 번호
- US07897627B2
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