Hydrochloric Acid → 2-Methoxy-6-methylbenzoic acid

HRID 611703

반응식

HRID 611703 반응식
[CH3:1][O:2][C:3]1[CH:13]=[CH:12][CH:11]=[C:10]([CH3:14])[C:4]=1[C:5]([O:7]CC)=[O:6].CO.[OH-].[Na+].Cl>O>[CH3:1][O:2][C:3]1[CH:13]=[CH:12][CH:11]=[C:10]([CH3:14])[C:4]=1[C:5]([OH:7])=[O:6]

참가 물질

6

반응물 4

HCID 313Hydrochloric AcidHCID 887MethanolHCID 14798Sodium HydroxideHCID 5910602-Methoxy-6-methyl-benzoic acid ethyl ester

생성물 1

HCID 2731702-Methoxy-6-methylbenzoic acid

시약·촉매·용매 1

HCID 962Water용매2회

실험 절차

A mixture of ethyl 2-methoxy-6-methylbenzoate (5.0 g, 25 mmol), water (10 ml), methanol (40 ml) and sodium hydroxide (2.1 g, 50 mmol) is heated under reflux with stirring. The reaction mixture is diluted with water (150 ml) and acidified with concentrated hydrochloric acid. The solid material is collected by filtration, washed with water and dried yielding dark yellow crystals, 2.1 g, mp 136° C.

후처리

  1. temperatureis heated
  2. temperatureunder reflux
  3. filtrationThe solid material is collected by filtration
  4. washwashed with water
  5. customdried
  6. customyielding dark yellow crystals, 2.1 g, mp 136° C.

출처 및 근거

ORD 기록
ord-c7f8dbd0b57f4d3ea9efe6be3a909883
출처 데이터셋
uspto-grants-1999_12
특허 번호
US06001883

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