Hydrochloric Acid → D-phenylalanine hydrochloride

HRID 613796

반응식

HRID 613796 반응식
[NH2:1][C@@H:2]([C:10]([OH:12])=[O:11])[CH2:3][C:4]1[CH:9]=[CH:8][CH:7]=[CH:6][CH:5]=1.[ClH:13]>>[ClH:13].[NH2:1][C@@H:2]([C:10]([OH:12])=[O:11])[CH2:3][C:4]1[CH:9]=[CH:8][CH:7]=[CH:6][CH:5]=1

참가 물질

3

반응물 2

HCID 313Hydrochloric AcidHCID 71567D-Phenylalanine

생성물 1

HCID 13000988D-phenylalanine hydrochloride

실험 절차

The residual mother liquor weighing 1359 g which contained 185.6 mmol of D-phenylalanine having an optical purity of 93.6% was adjusted to pH 0.5 with concentrated hydrochloric acid, and the resulting solution was concentrated until crystals began to precipitate to carry out crystallization. The aqueous slurry containing the crystals was filtered by suction at room temperature to give 74.8 mmol of glossy and grayish crystals of D-phenylalanine hydrochloride having an optical purity of 99.2%. The mother liquor contained 110.8 mmol of D-phenylalanine having an optical purity of 89.7%.

후처리

  1. concentrationthe resulting solution was concentrated until crystals
  2. customto precipitate
  3. customcrystallization
  4. additionThe aqueous slurry containing the crystals
  5. filtrationwas filtered by suction at room temperature

출처 및 근거

ORD 기록
ord-5ac1dc546b954f75a397be33b350b0c6
출처 데이터셋
uspto-grants-1999_12
특허 번호
US06008403

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