4-Methoxy-1-naphthol → HCID 178493282, 화합물

HRID 613946

반응식

HRID 613946 반응식
[NH2:1][C:2]1[CH:10]=[CH:9][C:5]2[NH:6][N:7]=[N:8][C:4]=2[CH:3]=1.[N:11]([O-])=O.[Na+].[CH3:15][O:16][C:17]1[C:26]2[C:21](=[CH:22][CH:23]=[CH:24][CH:25]=2)[C:20]([OH:27])=[CH:19][CH:18]=1.C([O-])(=O)C.[Na+]>Cl.O.[OH-].[Na+]>[NH:6]1[C:5]2[CH:9]=[CH:10][C:2]([N:1]=[N:11][C:19]3[CH:18]=[C:17]([O:16][CH3:15])[C:26]4[C:21](=[CH:22][CH:23]=[CH:24][CH:25]=4)[C:20]=3[OH:27])=[CH:3][C:4]=2[N:8]=[N:7]1

참가 물질

8

반응물 4

HCID 665424-Methoxy-1-naphtholHCID 517045Sodium AcetateHCID 23668193Sodium NitriteHCID 178507366HCID 178507366, 화합물

생성물 1

HCID 178493282HCID 178493282, 화합물수율 76.2%

시약·촉매·용매 3

HCID 313Hydrochloric Acid용매2회HCID 962Water용매2회HCID 14798Sodium Hydroxide용매

반응 조건

온도
0 °C

실험 절차

5-Aminobenzotriazole (4.3 g) was dissolved in a mixture of concentrated hydrochloric acid (24 ml) and water (100 ml) and diazotized at 0° C. with a solution of sodium nitrite (2.2 g) in water (15 ml). The resulting diazonium solution was added at 0° C. to 4-methoxynaphth-1-ol (5.3 g) dissolved in 3N sodium hydroxide (90 ml) containing sodium acetate (20 g). The resulting mixture was stirred for one hour at 0° C. and then acidified with hydrochloric acid. The dye was filtered off and crystallized in a pyridine/water mixture to give pure material (7.4 g), m.p. 254° C., λmax (methanol) = 516 nm.

후처리

  1. filtrationThe dye was filtered off
  2. customcrystallized in a pyridine/water mixture

출처 및 근거

ORD 기록
ord-c8629ea2a8474df5b6c6fd5a6a24503c
출처 데이터셋
uspto-grants-1979_03
특허 번호
US04142901

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