Hydrochloric Acid → HCID 13707639, 화합물
반응식
[N+:1]([C:4]1C(=O)[O:6][C:7]2[C:12]([C:13]=1[OH:14])=[CH:11][CH:10]=[C:9]([O:15][CH3:16])[CH:8]=2)([O-:3])=[O:2].Cl>[OH-].[Na+]>[OH:6][C:7]1[CH:8]=[C:9]([O:15][CH3:16])[CH:10]=[CH:11][C:12]=1[C:13](=[O:14])[CH2:4][N+:1]([O-:3])=[O:2]참가 물질
4
실험 절차
3-Nitro-4-hydroxy-7-methoxy coumarin (1.85 g, 0.078 m), prepared as described in D. R. Buckle, et al., J. Med. Chem., 18, 391 (1975), was stirred at room temperature in 5% aqueous sodium hydroxide (60 ml) for 20 hours. The mixture was slowly acidified with 5N HCl. The product was filtered off and sucked dry. Recrystallization from absolute ethanol gave pale yellow crystals (0.92 g, 56%), m.p. 138°-40° C.
후처리
- filtrationThe product was filtered off
- customsucked dry
- customRecrystallization from absolute ethanol
출처 및 근거
- ORD 기록
- ord-0623de98b3024ab3a46b4b01a12c3934
- 출처 데이터셋
- uspto-grants-1978_02
- 특허 번호
- US04076729
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