4-Hydroxybenzoic Acid → Ethenyl 4-hydroxybenzoate

HRID 619546노트

반응식

HRID 619546 반응식
[C:1]([O:4][CH:5]=[CH2:6])(=[O:3])[CH3:2].[OH:7][C:8]1[CH:16]=[CH:15]C(C(O)=O)=[CH:10][CH:9]=1.C([O-])(=O)C.[K+]>C([O-])(=O)C.[Pd+2].C([O-])(=O)C.ClCCl>[OH:7][C:8]1[CH:16]=[CH:15][C:2]([C:1]([O:4][CH:5]=[CH2:6])=[O:3])=[CH:10][CH:9]=1

참가 물질

6

반응물 3

HCID 1354-Hydroxybenzoic AcidHCID 7904Vinyl AcetateHCID 517044Potassium Acetate

생성물 1

HCID 13040874Ethenyl 4-hydroxybenzoate수율 10%

시약·촉매·용매 2

HCID 167845palladium(II) acetate촉매HCID 6344Dichloromethane용매

실험 절차

2000 g of dichloromethane, 24.9 g of vinyl acetate, 40.0 g of 4-hydroxybenzoic acid, 0.79 g of palladium acetate and 3.5 g of potassium acetate were charged into a separable flask of the same type as used in Reference Example 3 and subjected to reaction at 50° C. for 6 hours, while replacing the flask inside atomosphere with a nitrogen gas. After completion of the reaction, the reaction mixture was washed successively with an aqueous 0.5N sodium carbonate solution and water, and then treated in th same manner as in Reference Example 3, whereby 4.8 g of vinyl 4-hydroxybenzoate having the following chemical formula was obtained (yield: 10%): ##STR5##

후처리

  1. customsubjected to reaction at 50° C. for 6 hours
  2. customAfter completion of the reaction
  3. washthe reaction mixture was washed successively with an aqueous 0.5N sodium carbonate solution and water
  4. additiontreated in th same manner as in Reference Example 3, whereby 4.8 g of vinyl 4-hydroxybenzoate having the following chemical formula
  5. customwas obtained (yield: 10%)

출처 및 근거

ORD 기록
ord-12e3692588a84529baaa0f3f0cbb473a
출처 데이터셋
uspto-grants-1999_09
특허 번호
US05959037

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