Hydrochloric Acid → 4-(7-Octenyloxy)benzoic acid

HRID 6321

반응식

HRID 6321 반응식
Br[CH2:2][CH2:3][CH2:4][CH2:5][CH2:6][CH2:7][CH:8]=[CH2:9].[OH:10][C:11]1[CH:21]=[CH:20][C:14]([C:15]([O:17]CC)=[O:16])=[CH:13][CH:12]=1.C(=O)([O-])[O-].[K+].[K+].[OH-].[Na+].Cl>C(O)C.O>[CH2:2]([O:10][C:11]1[CH:21]=[CH:20][C:14]([C:15]([OH:17])=[O:16])=[CH:13][CH:12]=1)[CH2:3][CH2:4][CH2:5][CH2:6][CH2:7][CH:8]=[CH2:9]

참가 물질

8

반응물 5

HCID 313Hydrochloric AcidHCID 8434EthylparabenHCID 11430Potassium CarbonateHCID 14798Sodium HydroxideHCID 759078-Bromooct-1-ene

생성물 1

HCID 139976794-(7-Octenyloxy)benzoic acid수율 89%

시약·촉매·용매 2

HCID 702Ethanol용매HCID 962Water용매

실험 절차

9.4 g of 8-bromo-1-octene, 9.0 g of ethyl p-hydroxybenzoate, and 7.6 g of potassium carbonate were refluxed in ethanol for 10 hours. Added thereto was an aqueous solution containing 2.4 g of sodium hydroxide, and reflux was further continued for 10 hours. After conclusion of the reaction, the reaction solution was diluted with water, and the pH of the diluted solution was lowered to 2 by dropping hydrochloric acid thereto. The generated precipitate was collected, and was then washed with water sufficiently and dried, to obtain 10.8 g of the objective ether compound. (Yield: 89%)

후처리

  1. additionAdded
  2. temperaturereflux
  3. customAfter conclusion of the reaction
  4. customThe generated precipitate was collected
  5. washwas then washed with water sufficiently
  6. customdried
  7. customto obtain 10.8 g of the objective ether compound

출처 및 근거

ORD 기록
ord-ef446ce9b28342d0a62b3c6f5e5e4b49
출처 데이터셋
uspto-grants-1993_09
특허 번호
US05248446

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