Sodium Azide → 2-Phenoxy-2-oxo-6-(azidomethyl)-1,2-oxaphosphorinane
반응식
[N-:1]=[N+:2]=[N-:3].[Na+].[O:5]([P:12]1(=[O:20])[CH2:17][CH2:16][CH2:15][CH:14]([CH2:18]I)[O:13]1)[C:6]1[CH:11]=[CH:10][CH:9]=[CH:8][CH:7]=1>[Br-].C([N+](CCCC)(CCCC)CCCC)CCC.C1C=CC=CC=1.CN(C=O)C>[O:5]([P:12]1(=[O:20])[CH2:17][CH2:16][CH2:15][CH:14]([CH2:18][N:1]=[N+:2]=[N-:3])[O:13]1)[C:6]1[CH:7]=[CH:8][CH:9]=[CH:10][CH:11]=1참가 물질
5
실험 절차
A suspension containing two equivalents of sodium azide, one equivalent of the above-prepared iodonated oxaphosphorinane and a catalytic amount of about 0.1 equivalent of tetrabutylammonium bromide in benzene/DMF (1:1) was heated to 60-80 degrees C. for 16 hours to produce 2-phenoxy-2-oxo-6-(azidomethyl)-1,2-oxaphosphorinane in 96 percent yield as a white solid.
출처 및 근거
- ORD 기록
- ord-e5f02821feab4e68bc5f37db01f810ce
- 출처 데이터셋
- uspto-grants-1993_09
- 특허 번호
- US05248611
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