Hydrochloric Acid → 1'-methylspiro[indene-1,4'-piperidin]-3(2H)-one O-methyloxime

HRID 645598노트

반응식

HRID 645598 반응식
[CH3:1][N:2]1[CH2:7][CH2:6][C:5]2([C:15]3[C:10](=[CH:11][CH:12]=[CH:13][CH:14]=3)[C:9](=O)[CH2:8]2)[CH2:4][CH2:3]1.Cl.[O:18]([NH2:20])[CH3:19]>>[CH3:19][O:18][N:20]=[C:9]1[C:10]2[C:15](=[CH:14][CH:13]=[CH:12][CH:11]=2)[C:5]2([CH2:6][CH2:7][N:2]([CH3:1])[CH2:3][CH2:4]2)[CH2:8]1

참가 물질

4

반응물 3

HCID 313Hydrochloric AcidHCID 4113O-MethylhydroxylamineHCID 537128261'-methylspiro[indene-1,4'-piperidin]-3(2H)-one

생성물 1

HCID 860822791'-methylspiro[indene-1,4'-piperidin]-3(2H)-one O-methyloxime

실험 절차

The product of Example 138B and the HCl salt of methoxylamine were processed according to the method of Example 135A to provide the product. MS (ESI+) m/z 245 (M+H)+.

후처리

  1. customto provide the product

출처 및 근거

ORD 기록
ord-a22a447cb676450c9f2475c6b48afa54
출처 데이터셋
uspto-grants-2010_04
특허 번호
US07704997B1

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