Benzoyl Peroxide → 4-(4-Methoxybenzoyl)benzyl bromide

HRID 647798

반응식

HRID 647798 반응식
C(OOC(=O)C1C=CC=CC=1)(=O)C1C=CC=CC=1.[CH3:19][O:20][C:21]1[CH:26]=[CH:25][C:24]([C:27]([C:29]2[CH:34]=[CH:33][C:32]([CH3:35])=[CH:31][CH:30]=2)=[O:28])=[CH:23][CH:22]=1.[Br:36]N1C(=O)CCC1=O>C(Cl)(Cl)(Cl)Cl>[Br:36][CH2:35][C:32]1[CH:33]=[CH:34][C:29]([C:27]([C:24]2[CH:23]=[CH:22][C:21]([O:20][CH3:19])=[CH:26][CH:25]=2)=[O:28])=[CH:30][CH:31]=1

참가 물질

5

반응물 3

HCID 7187Benzoyl PeroxideHCID 32113(4-Methoxyphenyl)(4-methylphenyl)methanoneHCID 67184N-bromobutanimide

생성물 1

HCID 131506704-(4-Methoxybenzoyl)benzyl bromide수율 29.2%

시약·촉매·용매 1

HCID 5943Carbon Tetrachloride용매

실험 절차

Benzoyl peroxide (1 g) was added to a solution of 4-methoxyphenyl-4-methylphenyl methanone (22.6 g) and N-bromosuccinimide (17.8 g) in CCl4 (100 ml). The mixture was heated under reflux for 3.25 h, then cooled to 0°. The precipitated succinimide was filtered off, the filtrate evaporated and the residue purified by crystallisation from cyclohexane to give the title compound (8.9 g), m.p. 76°-78°.

후처리

  1. temperatureThe mixture was heated
  2. temperatureunder reflux for 3.25 h
  3. temperaturecooled to 0°
  4. filtrationThe precipitated succinimide was filtered off
  5. customthe filtrate evaporated
  6. customthe residue purified by crystallisation from cyclohexane

출처 및 근거

ORD 기록
ord-0b787cae83ac48669327f043bb8ae569
출처 데이터셋
uspto-grants-1983_10
특허 번호
US04410521

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