Hydrochloric Acid → 5-(2-Formyl-3-hydroxy-4-carboxyphenoxy)pentanoic acid

HRID 647903

반응식

HRID 647903 반응식
[CH:1]([C:3]1[C:18]([OH:19])=[C:17]([C:20]([O:22]C)=[O:21])[CH:16]=[CH:15][C:4]=1[O:5][CH2:6][CH2:7][CH2:8][CH2:9][C:10]([O:12]CC)=[O:11])=[O:2].Cl>[OH-].[Na+]>[CH:1]([C:3]1[C:18]([OH:19])=[C:17]([C:20]([OH:22])=[O:21])[CH:16]=[CH:15][C:4]=1[O:5][CH2:6][CH2:7][CH2:8][CH2:9][C:10]([OH:12])=[O:11])=[O:2]

참가 물질

4

반응물 2

HCID 313Hydrochloric AcidHCID 20484347Ethyl 5-(2-formyl-3-hydroxy-4-methoxycarbonylphenoxy)pentanoate

생성물 1

HCID 204843435-(2-Formyl-3-hydroxy-4-carboxyphenoxy)pentanoic acid

시약·촉매·용매 1

HCID 14798Sodium Hydroxide용매

실험 절차

Ethyl 5-(2-formyl-3-hydroxy-4-methoxycarbonylphenoxy)pentanoate (0.5 g, 0.0015 M) was added to 10% sodium hydroxide solution (10 ml) and stirred at room temperature for 2 hours. The reaction mixture was acidified with concentrated hydrochloric acid and the resulting solid was filtered, sucked dry, and washed with a little ethanol, then dried in a desiccator over phosphorus pentoxide to give 5-(2-formyl-3-hydroxy-4-carboxyphenoxy)pentanoic acid, 0.38 g, 90%, m.p. 165°-166° C.

후처리

  1. filtrationthe resulting solid was filtered
  2. customsucked dry
  3. washwashed with a little ethanol
  4. dry with materialdried in a desiccator over phosphorus pentoxide

출처 및 근거

ORD 기록
ord-5b63541196f04a7e8ac0a2bb42f7ddd6
출처 데이터셋
uspto-grants-1983_10
특허 번호
US04410537

연결된 노트

불러오는 중…