3-Aminobenzoic Acid → 3-[(Pyridin-4-yl)amino]benzoic acid

HRID 64895

반응식

HRID 64895 반응식
[NH2:1][C:2]1[CH:3]=[C:4]([CH:8]=[CH:9][CH:10]=1)[C:5]([OH:7])=[O:6].Cl[C:12]1[CH:17]=[CH:16][N:15]=[CH:14][CH:13]=1>C(O)(=O)C>[N:15]1[CH:16]=[CH:17][C:12]([NH:1][C:2]2[CH:3]=[C:4]([CH:8]=[CH:9][CH:10]=2)[C:5]([OH:7])=[O:6])=[CH:13][CH:14]=1

참가 물질

4

반응물 2

HCID 74193-Aminobenzoic AcidHCID 122884-Chloropyridine

생성물 1

HCID 137124753-[(Pyridin-4-yl)amino]benzoic acid

시약·촉매·용매 1

HCID 176Acetic Acid용매

실험 절차

3-(4-Pyridinylamino)benzoic acid was prepared from 41.1 g of m-aminobenzoic acid and 34.0 g of 4-chloropyridine in 110 ml of acetic acid, heated at reflux for 6 hours. With a work-up procedure similar to that of Example 33, there was obtained 48.5 g of product, m.p. 172°-180° C.

후처리

  1. temperatureheated
  2. temperatureat reflux for 6 hours

출처 및 근거

ORD 기록
ord-dd186632b4854b4aa65d99b84bc932a3
출처 데이터셋
uspto-grants-1986_09
특허 번호
US04610991

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