Hydrochloric Acid → 2-Chloro-3-fluoroaniline

HRID 65733

반응식

HRID 65733 반응식
[Cl:1][C:2]1[C:7]([F:8])=[CH:6][CH:5]=[CH:4][C:3]=1[N+:9]([O-])=O.Cl.[OH-].[Na+]>>[Cl:1][C:2]1[C:7]([F:8])=[CH:6][CH:5]=[CH:4][C:3]=1[NH2:9]

참가 물질

4

반응물 3

HCID 313Hydrochloric AcidHCID 14798Sodium HydroxideHCID 888832-Chloro-1-fluoro-3-nitrobenzene

생성물 1

HCID 888842-Chloro-3-fluoroaniline

실험 절차

19.6 g. of 2-chloro-3-fluoronitrobenzene (0.11 mole) is reduced with stannous chloride (118 g., 0.63 mole) in 180 ml. of concentrated hydrochloric acid. The solution is basified with aqueous sodium hydroxide and extracted with chloroform to yield 2-chloro-3-fluoroaniline.

후처리

  1. extractionextracted with chloroform

출처 및 근거

ORD 기록
ord-1db00a5a9136416fb08e3a530f59cd2f
출처 데이터셋
uspto-grants-1978_12
특허 번호
US04128666

연결된 노트

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