Catechol → o-(1-Methoxyethoxy)-phenol
반응식
[C:1]1([C:3](=[CH:5][CH:6]=[CH:7][CH:8]=1)[OH:4])[OH:2].[CH:9]([O:11][CH3:12])=[CH2:10].Cl.[OH-].[Na+]>C1(C)C=CC=CC=1>[CH3:12][O:11][CH:9]([O:2][C:1]1[CH:8]=[CH:7][CH:6]=[CH:5][C:3]=1[OH:4])[CH3:10]참가 물질
6
실험 절차
110 parts by weight of pyrocatechol is suspended in 100 parts by weight of toluene. At +5° C., 64 parts by weight of vinylmethyl ether at -40° C. is introduced all at once into the suspension and a drop of concentrated hydrochloric acid is then added. The mixture is heated, with stirring, to about +20° C., whereupon the reaction is initiated and the temperature in the flask rises to about 65° C. If necessary, ice water may be used for external cooling. The mixture is kept for 30 minutes at 65° C. and 5 parts by weight of 2N NaOH is then added. After the mixture has been cooled and dried with Na2SO4 the solvent is evaporated in a rotary evaporator and distillation carried out in vacuo.