Hydrochloric Acid → (2R,4S)-4-[(3,5-Bis-trifluoromethyl-benzyl)-(5-morpholin-4-yl-pyridin-2-yl)-amino]-2-ethyl-6-trifluoromethyl-3,4-dihydro-2H-quinoline-1-carboxylic acid 2-tert-butoxycarbonyl-2-methyl-propyl ester

반응식

[C:1]([O:5][C:6]([C:8]([CH3:43])([CH3:42])[CH2:9][O:10][C:11]([N:13]1[C:22]2[C:17](=[CH:18][C:19]([C:23]([F:26])([F:25])[F:24])=[CH:20][CH:21]=2)[C@@H:16]([NH:27][C:28]2[CH:33]=[CH:32][C:31]([N:34]3[CH2:39][CH2:38][O:37][CH2:36][CH2:35]3)=[CH:30][N:29]=2)[CH2:15][C@H:14]1[CH2:40][CH3:41])=[O:12])=[O:7])([CH3:4])([CH3:3])[CH3:2].[F:44][C:45]([F:59])([F:58])[C:46]1[CH:47]=[C:48]([CH:51]=[C:52]([C:54]([F:57])([F:56])[F:55])[CH:53]=1)[CH2:49]Br.Cl.C(OCC)(=O)C>[I-].C([N+](CCCC)(CCCC)CCCC)CCC.COC(C)(C)C>[C:1]([O:5][C:6]([C:8]([CH3:42])([CH3:43])[CH2:9][O:10][C:11]([N:13]1[C:22]2[C:17](=[CH:18][C:19]([C:23]([F:25])([F:24])[F:26])=[CH:20][CH:21]=2)[C@@H:16]([N:27]([CH2:49][C:48]2[CH:51]=[C:52]([C:54]([F:56])([F:57])[F:55])[CH:53]=[C:46]([C:45]([F:44])([F:58])[F:59])[CH:47]=2)[C:28]2[CH:33]=[CH:32][C:31]([N:34]3[CH2:35][CH2:36][O:37][CH2:38][CH2:39]3)=[CH:30][N:29]=2)[CH2:15][C@H:14]1[CH2:40][CH3:41])=[O:12])=[O:7])([CH3:4])([CH3:3])[CH3:2]