Tetramethylammonium fluoride → HCID 66687330, 화합물

HRID 661556

반응식

[C:1]([O:5][C:6]([N:8]1[CH2:12][CH:11]([O:13][Si](C(C)(C)C)(C)C)[CH2:10][C@:9]1([CH2:31][CH2:32][CH3:33])[C:21](=[O:30])[C:22]1[CH:27]=[CH:26][C:25]([Cl:28])=[C:24]([Cl:29])[CH:23]=1)=[O:7])([CH3:4])([CH3:3])[CH3:2].C[N+](C)(C)C.[F-]>>[C:1]([O:5][C:6]([N:8]1[CH2:12][CH:11]([OH:13])[CH2:10][C@@:9]1([C:21](=[O:30])[C:22]1[CH:27]=[CH:26][C:25]([Cl:28])=[C:24]([Cl:29])[CH:23]=1)[CH2:31][CH2:32][CH3:33])=[O:7])([CH3:2])([CH3:3])[CH3:4]

참가 물질

반응물 2

HCID 67803Tetramethylammonium fluoride

HCID 66687873HCID 66687873, 화합물

생성물 1

HCID 66687330HCID 66687330, 화합물

실험 절차

(R)-2-(3,4-Dichloro-benzoyl)-4-hydroxy-2-propyl-pyrrolidine-1-carboxylic acid tert-butyl ester was prepared by treating (R)-4-(tert-Butyl-dimethyl-silanyloxy)-2-propyl-2-(3,4-dichloro-benzoyl)-pyrrolidine-1-carboxylic acid tert-butyl ester with TMAF following the procedure of step 3 of Example 11.

출처 및 근거

ORD 기록: ord-b2754af559cd48a8b65f0ac3684c5f71
출처 데이터셋: uspto-grants-2011_12
DOI: 10.6084/m9.figshare.5104873.v1
특허 번호: US08084623B2

연결된 노트

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