Dimethyl Sulfoxide → 2-(4-Chlorophenoxy)acetonitrile
반응식
[Cl:1][C:2]1[CH:7]=[CH:6][C:5]([OH:8])=[CH:4][CH:3]=1.C(=O)([O-])[O-].[K+].[K+].Cl[CH2:16][C:17]#[N:18].CS(C)=O>O>[Cl:1][C:2]1[CH:7]=[CH:6][C:5]([O:8][CH2:16][C:17]#[N:18])=[CH:4][CH:3]=1참가 물질
6
실험 절차
A mixture of 64.25 g of 4-chlorophenol, 98 g of anhydrous potassium carbonate, 40 g of chloroacetonitrile and 100 ml of dimethyl sulfoxide was heated with stirring in a 500 ml round-bottomed three-necked flask at 70°-80° C. for 3.0 hours. The reaction mixture was then poured into ice and water. After the ice melted, the mixture was filtered and the product washed well with water which gave 77.5 g of 4-chlorophenoxyacetonitrile.
후처리
- temperaturewas heated
- filtrationthe mixture was filtered
- washthe product washed well with water which
출처 및 근거
- ORD 기록
- ord-9c18c5a5f562428fb1f2d2a6984cc88c
- 출처 데이터셋
- uspto-grants-1982_08
- 특허 번호
- US04343809
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