2-Pentanone → 1-Bromo-trans-1-octen-3-one

HRID 66999

반응식

HRID 66999 반응식
Cl/[CH:2]=[CH:3]/[C:4](=[O:10])[CH2:5][CH2:6][CH2:7][CH2:8][CH3:9].[Br-:11].[Li+].CC(=O)CCC>>[Br:11]/[CH:2]=[CH:3]/[C:4](=[O:10])[CH2:5][CH2:6][CH2:7][CH2:8][CH3:9]

참가 물질

4

반응물 3

HCID 78952-PentanoneHCID 82050Lithium BromideHCID 110410031-Chloro-trans-1-octen-3-one

생성물 1

HCID 117903381-Bromo-trans-1-octen-3-one

실험 절차

A mixture of 68.0 g. (0.424 mole) of 1-chloro-trans-1-octen-3 one (Example 723) and 444 g. (4.24 moles) of anhydrous lithium bromide in 900 ml. of 2-pentanone is refluxed for 30 minutes, cooled, and partitioned between ice water and ether. The organic phase is washed with water and saturated brine, dried (NaSO4), and evaporated to an oil. This material is used directly without purification.

후처리

  1. additionA mixture of 68.0 g
  2. temperaturecooled
  3. custompartitioned between ice water and ether
  4. washThe organic phase is washed with water and saturated brine
  5. dry with materialdried (NaSO4)
  6. customevaporated to an oil
  7. customThis material is used directly without purification

출처 및 근거

ORD 기록
ord-8fa867cbcf20417ab9d4d032eb2d0c3c
출처 데이터셋
uspto-grants-1982_08
특허 번호
US04343949

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