Sodium Hydroxide → N-Methyl-N'-phenylcarbodiimide

HRID 67784

반응식

HRID 67784 반응식
Cl.[CH3:2][NH:3][C:4](Cl)=[N:5][C:6]1[CH:11]=[CH:10][CH:9]=[CH:8][CH:7]=1.[OH-].[Na+]>C(Cl)(Cl)Cl>[CH3:2][N:3]=[C:4]=[N:5][C:6]1[CH:11]=[CH:10][CH:9]=[CH:8][CH:7]=1

참가 물질

4

반응물 2

HCID 14798Sodium HydroxideHCID 178484191HCID 178484191, 화합물

생성물 1

HCID 138144N-Methyl-N'-phenylcarbodiimide

시약·촉매·용매 1

HCID 6212Chloroform용매

실험 절차

A suspension of 2.05 g of N-methyl-N'-phenylchloroformamidine hydrochloride in 8 ml of chloroform is added, at 10°-12° C., to 6 g of 20% strength sodium hydroxide solution. The mixture is stirred for 10 minutes, the organic phase is separated off, the aqueous phase is extracted twice more with chloroform and the combined organic phases are dried over K2CO3. After filtering off the desiccant, the solution is subjected to further reaction without isolating the carbodiimide.

후처리

  1. customthe organic phase is separated off
  2. extractionthe aqueous phase is extracted twice more with chloroform
  3. dry with materialthe combined organic phases are dried over K2CO3
  4. filtrationAfter filtering off the desiccant
  5. customthe solution is subjected to further reaction

출처 및 근거

ORD 기록
ord-f25a5706316a4c30a4802f436981a3a1
출처 데이터셋
uspto-grants-1982_08
특허 번호
US04346088

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