Tetrahydrofuran → Tert-butyl 4-(2-fluoro-3-(3-(2-methylpyridin-4-yl)ureido)benzyl)piperazine-1-carboxylate

HRID 686697

반응식

[CH2:52]1[O:53][CH2:54][CH2:55][CH2:56]1.[CH3:57][CH2:58][O:59][C:60]([CH3:61])=[O:62].[CH:35]([N:36]([CH2:37][CH3:38])[CH:39]([CH3:40])[CH3:41])([CH3:42])[CH3:43].[Cl:1][C:2]([Cl:3])([O:4][C:5]([O:6][C:7]([Cl:8])([Cl:9])[Cl:10])=[O:11])[Cl:12].[NH2:13][c:14]1[c:15]([F:34])[c:16]([CH2:17][N:18]2[CH2:19][CH2:20][N:21]([C:24](=[O:25])[O:26][C:27]([CH3:28])([CH3:29])[CH3:30])[CH2:22][CH2:23]2)[cH:31][cH:32][cH:33]1.[NH2:44][c:45]1[cH:46][c:47]([CH3:51])[n:48][cH:49][cH:50]1>>[C:5](=[O:11])([NH:13][c:14]1[c:15]([F:34])[c:16]([CH2:17][N:18]2[CH2:19][CH2:20][N:21]([C:24](=[O:25])[O:26][C:27]([CH3:28])([CH3:29])[CH3:30])[CH2:22][CH2:23]2)[cH:31][cH:32][cH:33]1)[NH:44][c:45]1[cH:46][c:47]([CH3:51])[n:48][cH:49][cH:50]1